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1

Correlation between net water flux and absorptive clearance determined from in situ intestinal perfusion studies does not necessarily indicate a solvent drag effect

Zheng Yang, Guanfa Gan, Ronald J. Sawchuk

Journal:

Journal of Pharmaceutical Sciences

Year:

2007

Language:

english

File:

PDF, 105 KB

english, 2007

2

Pharmacokinetics of dosing regimens which utilize multiple intravenous infusions: Gentamicin in burn patients

Ronald J. Sawchuk, Darwin E. Zaske

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1976

Language:

english

File:

PDF, 581 KB

english, 1976

3

Disgust sensitivity and contamination fears in spider and blood–injection–injury phobias

Craig N Sawchuk, Jeffrey M Lohr, David F Tolin, Thomas C Lee, Ronald A Kleinknecht

Journal:

Behaviour Research and Therapy

Year:

2000

Language:

english

File:

PDF, 108 KB

english, 2000

4

Transsynovial Drug Distribution: Synovial Mean Transit Time of Diclofenac and Other Nonsteroidal Antiinflammatory Drugs

William F. Elmquist, Keith K. H. Chan, Ronald J. Sawchuk

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.31 MB

1994

5

Kinetic model for gentamicin dosing with the use of individual patient parameters

Sawchuk, Ronald J., Zaske, Darwin E., Cipolle, Robert J., Wargin, William A., Strate, Richard G.

Journal:

Clinical Pharmacology & Therapeutics

Year:

1977

Language:

english

File:

PDF, 1.12 MB

english, 1977

6

Human pharmacokinetics of the antiviral drug DHPG

Fletcher, Courtney, Sawchuk, Ronald, Chinnock, Barbara, de Miranda, Paulo, Balfour, Henry H

Journal:

Clinical Pharmacology & Therapeutics

Year:

1986

Language:

english

File:

PDF, 501 KB

english, 1986

7

Pharmacokinetics of propylene glycol in humans during multiple dosing regimens

Dale K. Yu, William F. Elmquist, Ronald J. Sawchuk

Journal:

Journal of Pharmaceutical Sciences

Year:

1985

Language:

english

File:

PDF, 401 KB

english, 1985

8

A partial area difference analysis for estimating elimination rate constants and distribution volumes of metabolites

Lillian E. Riad, Ronald J. Sawchuk

Journal:

Journal of Pharmaceutical Sciences

Year:

1998

Language:

english

File:

PDF, 80 KB

english, 1998

9

Application of Microdialysis in Pharmacokinetic Studies

William F. Elmquist, Ronald J. Sawchuk

Journal:

Pharmaceutical Research

Year:

1997

File:

PDF, 2.50 MB

1997

10

Clinical Sevoflurane Metabolism and Disposition

Kharasch, Evan D., Karol, Michael D., Lanni, Carmine, Sawchuk, Ronald

Journal:

Year:

1995

File:

PDF, 6.97 MB

1995

11

Increased Clearance of Phenytoin during Infectious Mononucleosis

Leppik, Ilo E., Ramani, Venkat, Sawchuk, Ronald J., Gumnit, Robert J.

Journal:

Boston Medical and Surgical Journal

Year:

1979

File:

PDF, 353 KB

1979

12

Compliance and Variability of Plasma Phenytoin Levels in Epileptic Patients

Leppik, Ilo E., Cloyd, James C., Sawchuk, Ronald J., Pepin, Steven M.

Journal:

Therapeutic Drug Monitoring

Year:

1979

File:

PDF, 346 KB

1979

13

In vitro–in vivo correlation and dissolution studies with oral theophylline dosage forms

Adnan El-Yazigi, Ronald J. Sawchuk

Journal:

Journal of Pharmaceutical Sciences

Year:

1985

Language:

english

File:

PDF, 461 KB

english, 1985

14

Effect of probenecid on the renal and nonrenal clearances of zidovudine and its distribution into cerebrospinal fluid in the rabbit

Mohsen A. Hedaya, Ronald J. Sawchuk

Journal:

Journal of Pharmaceutical Sciences

Year:

1989

Language:

english

File:

PDF, 881 KB

english, 1989

15

Analysis of Zidovudine Distribution to Specific Regions in Rabbit Brain Using Microdialysis

Shekman L. Wong, Yanfeng Wang, Ronald J. Sawchuk

Journal:

Pharmaceutical Research

Year:

1992

File:

PDF, 1.23 MB

1992

16

Pharmacokinetics and Metabolism of Diclofenac Sodium in Yucatan Miniature Pigs

Rebecca L. Oberle, Helena Das, Shekman L. Wong, Keith K. H. Chan, Ronald J. Sawchuk

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.14 MB

1994

17

The chinchilla microdialysis model for the study of antibiotic distribution to middle ear fluid

Belinda W. Y. Cheung, Wei Liu, Ping Ji, Linda L. Cartier, Zhihong Li, Nael Mostafa, Ronald J. Sawchuk

Journal:

The AAPS Journal

Year:

2006

Language:

english

File:

PDF, 294 KB

english, 2006

18

Simultaneous intravenous and intramiddle-ear dosing to determine cefditoren influx and efflux clearances in middle ear fluid in freely moving chinchillas

Tong Zhu, Belinda W.Y. Cheung, Linda L. Cartier, G. Scott Giebink, Ronald J. Sawchuk

Journal:

Journal of Pharmaceutical Sciences

Year:

2003

Language:

english

File:

PDF, 219 KB

english, 2003

19

INCREASED DOSAGE REQUIREMENTS OF GENTAMICIN IN BURN PATIENTS

ZASKE, DARWIN E., SAWCHUK, RONALD J., GERDING, DALE N., STRATE, RICHARD G.

Journal:

The Journal of Trauma Injury Infection and Critical Care

Year:

1976

File:

PDF, 297 KB

1976

20

Transaqueous diffusion of acetylcholine to denervated iris sphincter muscle: A mechanism for the tonic pupil syndrome (adie syndrome)

Dr. Jonathan D. Wirtschafter, Charles R. Volk, Ronald J. Sawchuk

Journal:

Annals of Neurology

Year:

1978

Language:

english

File:

PDF, 492 KB

english, 1978

21

Severe methanol poisoning: Application of a pharmacokinetic model for ethanol therapy and hemodialysis

Harry G. McCoy, Robert J. Cipolle, Sally M. Ehlers, Ronald J. Sawchuk, Darwin E. Zaske

Journal:

The American Journal of Medicine

Year:

1979

Language:

english

File:

PDF, 488 KB

english, 1979

22

Vancomycin pharmacokinetics

Danial Baker, John C. Rotschafer, Ronald Sawchuk, Kent B. Crossley, Lynn D. Solem

Journal:

The Journal of Pediatrics

Year:

1980

Language:

english

File:

PDF, 180 KB

english, 1980

23

Microdialysis studies of the middle ear distribution kinetics of amoxicillin in the awake chinchilla

Yue Huang, Ping Ji, Akihiro Inano, Zheng Yang, G. Scott Giebink, Ronald J. Sawchuk

Journal:

Journal of Pharmaceutical Sciences

Year:

2001

Language:

english

File:

PDF, 211 KB

english, 2001

24

Theophylline absorption and disposition in rabbits: Oral, intravenous, and concentration-dependent kinetic studies

Adnan El-Yazigi, Ronald J. Sawchuk

Journal:

Journal of Pharmaceutical Sciences

Year:

1981

Language:

english

File:

PDF, 587 KB

english, 1981

25

The Relationship Between Urine and Plasma Concentrations of Carbamazepine: Implications for Therapeutic Drug Monitoring

William F. Elmquist, Lillian E. Riad, Ilo E. Leppik, Ronald J. Sawchuk

Journal:

Pharmaceutical Research

Year:

1991

File:

PDF, 384 KB

1991

26

Intravenous and oral pharmacokinetic evaluation of a 2-hydroxypropyl-β-cyclodextrin-based formulation of carbamazepine in the dog: Comparison with commercially available tablets and suspensions

Marcus E. Brewster, Wesley R. Anderson, Donald Meinsma, Daniel Moreno, Alistair I. Webb, Luisito Pablo, Kerry S. Estes, Hartmut Derendorf, Nicholas Bodor, Ronald Sawchuk, Belinda Cheung, Emil Pop

Journal:

Journal of Pharmaceutical Sciences

Year:

1997

Language:

english

File:

PDF, 295 KB

english, 1997

27

Drug Kinetics in Burn Patients

Ronald J. Sawchuk,Tom S. Rector

Journal:

Clinical Pharmacokinetics

Year:

1980

Language:

english

File:

PDF, 1.01 MB

english, 1980

28

Investigation of distribution, transport and uptake of anti-HIV drugs to the central nervous system

Ronald J. Sawchuk, Zheng Yang

Journal:

Advanced Drug Delivery Reviews

Year:

1999

Language:

english

File:

PDF, 198 KB

english, 1999

29

Absorption of cyclosporine from rabbit small intestine in situ

Ronald J. Sawchuk, Walid M. Awni

Journal:

Journal of Pharmaceutical Sciences

Year:

1986

Language:

english

File:

PDF, 570 KB

english, 1986

30

High-Performance Liquid Chromatographic Determination of 2′, 3′ -Didehydro-3′ -deoxythymidine (d4T) in Human and Rabbit Plasma and Urine and Its Application to Pharmacokinetic Studies in the Rabbit

Shekman L. Wong, Ronald J. Sawchuk

Journal:

Pharmaceutical Research

Year:

1991

File:

PDF, 887 KB

1991

31

Rapid and slow release phenytoin in epileptic patients at steady state: Comparative plasma levels and toxicity

Ronald J. Sawchuk, Steven M. Pepin, Ilo E. Leppik, Robert J. Gumnit

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1982

Language:

english

File:

PDF, 782 KB

english, 1982

32

Microdialysis in the study of drug transporters in the CNS

Ronald J Sawchuk, William F Elmquist

Journal:

Advanced Drug Delivery Reviews

Year:

2000

Language:

english

File:

PDF, 99 KB

english, 2000

33

EFFECT OF FOOD ON THE MULTIPLE-PEAK BEHAVIOR AFTER A SINGLE ORAL DOSE OF DICLOFENAC SODIUM SLOW-RELEASE TABLET IN HUMANS

Riad, Lillian E., Sawchuk, Ronald J., McAlary, Margaret M., Chan, Keith K.H.

Journal:

American Journal of Therapeutics

Year:

1995

File:

PDF, 432 KB

1995

34

Intestinal absorption and presystemic elimination of the prokinetic agent, EM574, in the rabbit

Guanfa Gan, Linda L. Cartier, Yue Huang, Zheng Yang, Ronald J. Sawchuk

Journal:

Journal of Pharmaceutical Sciences

Year:

2002

Language:

english

File:

PDF, 189 KB

english, 2002

35

Microdialysis Calibration Using Retrodialysis and Zero-Net Flux: Application to a Study of the Distribution of Zidovudine to Rabbit Cerebrospinal Fluid and Thalamus

Yanfeng Wang, Shekman L. Wong, Ronald J. Sawchuk

Journal:

Pharmaceutical Research

Year:

1993

File:

PDF, 1.63 MB

1993

36

Competitive Inhibition of Zidovudine Clearance by Probenecid During Continuous Coadministration

Shekman L. Wong, Mohsen A. Hedaya, Ronald J. Sawchuk

Journal:

Pharmaceutical Research

Year:

1992

File:

PDF, 1.35 MB

1992

37

Rapid and slow release phenytoin in epileptic patients at steady state: Assessment of relative bioavailability utilizing Michaelis-Menten parameters

Ronald J. Sawchuk, Steven M. Pepin, Ilo E. Leppik, Robert J. Gumnit

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1982

Language:

english

File:

PDF, 463 KB

english, 1982

38

Use of microdialysis in drug delivery studies

William F Elmquist, Ronald J Sawchuk

Journal:

Advanced Drug Delivery Reviews

Year:

2000

Language:

english

File:

PDF, 41 KB

english, 2000

39

The application of sample pooling methods for determining AUC, AUMC and mean residence times in pharmacokinetic studies

Belinda W.Y. Cheung, Linda L. Cartier, Henry Q. Russlie, Ronald J. Sawchuk

Journal:

Fundamental & Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 189 KB

english, 2005

40

The Blood–Brain Barrier and Drug Delivery to the CNS: D.J. Begley, M.W. Bradbury and J Kreuter, editors. M. Dekker, New York, 2000, 248 pages.

Ronald J. Sawchuk

Journal:

Journal of Controlled Release

Year:

2003

Language:

english

File:

PDF, 30 KB

english, 2003

41

Microdialysis Studies of the Distribution of Antibiotics into Chinchilla Middle Ear Fluid

Dr. Ronald J. Sawchuk, Belinda W. Y. Cheung, Ping Ji, Ms. Linda L. Cartier

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

2005

Language:

english

File:

PDF, 770 KB

english, 2005

42

Effect of Influenza Vaccination on Plasma Phenytoin Concentrations1

Sawchuk, Ronald J., Rector, Tom S., Fordice, John J., Leppik, Ilo E.

Journal:

Therapeutic Drug Monitoring

Year:

1979

File:

PDF, 1.52 MB

1979

43

Steady-state plasma concentrations as a function of the absorption rate and dosing interval for drugs exhibiting concentration-dependent clearance: Consequences for phenytoin therapy

Ronald J. Sawchuk, Tom S. Rector

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1979

Language:

english

File:

PDF, 620 KB

english, 1979

44

Impaired Phenytoin Bioavailability Secondary to Cisplatinum, Vinblastine, and Bleomycin

Sylvester, Robert K., Lewis, F. Bruce, Caldwell, Kenneth C., Lobell, Michael, Perri, Robert, Sawchuk, Ronald A.

Journal:

Therapeutic Drug Monitoring

Year:

1984

File:

PDF, 320 KB

1984

45

Pharmacokinetic model for subcutaneous absorption of cyclosporine in the rabbit during chronic treatment

Ajit K. Shah, Richard C. Brundage, Alois Gratwohl, Ronald J. Sawchuk

Journal:

Journal of Pharmaceutical Sciences

Year:

1992

Language:

english

File:

PDF, 531 KB

english, 1992

46

Microdialysis Studies of the Distribution of Stavudine into the Central Nervous System in the Freely-Moving Rat

Zheng Yang, Richard C. Brundage, Rashmi H. Barbhaiya, Ronald J. Sawchuk

Journal:

Pharmaceutical Research

Year:

1997

File:

PDF, 616 KB

1997

47

American ginseng. III. Pharmacokinetics of ginsenosides in the rabbit

S. Edith Chen, Ronald J. Sawchuk, E. John Staba

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

1980

Language:

english

File:

PDF, 894 KB

english, 1980

48

Probenecid Inhibits the Metabolic and Renal Clearances of Zidovudine (AZT) in Human Volunteers

Mohsen A. Hedaya, William F. Elmquist, Ronald J. Sawchuk

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 1.08 MB

1990

49

A Sensitive and Specific Liquid-Chromatographic Assay for Determination of Ganciclovir in Plasma and Urine and Its Application to Pharmacokinetic Studies in the Rabbit

Mohsen A. Hedaya, Ronald J. Sawchuk

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 902 KB

1990

50

Effect of co-administration of intralipidTM on the pharmacokinetics of cyclosporine in the rabbit

Ajit K. Shah, Ronald J. Sawchuk

Journal:

Biopharmaceutics & Drug Disposition

Year:

1991

Language:

english

File:

PDF, 498 KB

english, 1991

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